Autologous Fixed Tumor Vaccine: A Formulation with Cytokine‐microparticles for Protective Immunity against Recurrence of Human Hepatocellular Carcinoma

We developed a tumor vaccine consisting of fixed hepatocellular carcinoma (HCC) cells/tissue fragments, biodegradable microparticles encapsulating granulocyte‐macrophage‐colony stimulating factor and interleukin‐2, and an adjuvant. The vaccine protected 33% of syngeneic mice from HCC cell challenge....

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Peng, Bao Gang, Liu, Shu Qin, Kuang, Ming, He, Qiang, Totsuka, Saeri, Huang, Lan, Huang, Jiefu, Lu, Ming‐De, Liang, Li‐Jiang, Leong, Kam W., Ohno, Tadao
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2002
Assuntos:
Rapid Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5927015/
https://ncbi.nlm.nih.gov/pubmed/11985784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2002.tb01265.x
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