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Lack of Direct Involvement of 8‐Hydroxy‐2′‐deoxyguanosine in Hypoxanthine‐guanine Phosphoribosyltransferase Mutagenesis in V79 Cells Treated with N,N'‐Bis(2‐hydroxyperoxy‐2‐methoxyethyl)‐l,4,5,8‐naphthalenetetracarboxylic‐diimide (NP‐III) or Riboflavin

The object of this study is to investigate the relationship between a typical product of oxidative DNA damage, 8‐hydroxy‐2′‐deoxyguanosine (8OHdG), and mutagenesis in V79 cells through a molecular analysis of hypoxanthine‐guanine phosphoribosyltransferase (hprt) gene mutants. We performed a direct s...

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Détails bibliographiques
Publié dans:Jpn J Cancer Res
Auteurs principaux: Nakajima, Madoka, Takeuchi, Toru, Ogino, Keiki, Morimoto, Kanehisa
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926961/
https://ncbi.nlm.nih.gov/pubmed/11927005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2002.tb02165.x
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