TNF and granulocyte macrophage-colony stimulating factor interdependence mediates inflammation via CCL17

TNF and granulocyte macrophage-colony stimulating factor (GM-CSF) have proinflammatory activity and both contribute, for example, to rheumatoid arthritis pathogenesis. We previously identified a new GM-CSF→JMJD3 demethylase→interferon regulatory factor 4 (IRF4)→CCL17 pathway that is active in monocy...

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Bibliografische gegevens
Gepubliceerd in:JCI Insight
Hoofdauteurs: Cook, Andrew D., Lee, Ming-Chin, Saleh, Reem, Khiew, Hsu-Wei, Christensen, Anne D., Achuthan, Adrian, Fleetwood, Andrew J., Lacey, Derek C., Smith, Julia E., Förster, Irmgard, Hamilton, John A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2018
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926922/
https://ncbi.nlm.nih.gov/pubmed/29563337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99249
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