Close Correlation of 1‐β‐D‐Arabinofuranosylcytosine 5′‐Triphosphate, an Intracellular Active Metabolite, to the Therapeutic Efficacy of N(4)‐Behenoyl‐1‐β‐D‐arabinofuranosylcytosine Therapy for Acute Myelogenous Leukemia

N(4)‐Behenoyl‐l‐β‐D‐arabinofuranosylcytosine (BHAC), a prodrug of 1‐β ‐D‐arabinofuranosylcy‐tosine, is used effectively for the treatment of leukemia in Japan. BHAC therapy may be more effective if it is delivered in conjunction with monitoring of 1‐β ‐D‐arabinofuranosylcytosine 5′‐tri‐phosphate (ar...

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Détails bibliographiques
Publié dans:Jpn J Cancer Res
Auteurs principaux: Yamauchi, Takahiro, Kawai, Yasukazu, Goto, Nobuyuki, Kishi, Shinji, Imamura, Shin, Yoshida, Akira, Urasaki, Yoshimasa, Fukushima, Toshihiro, Iwasaki, Hiromichi, Tsutani, Hiroshi, Masada, Mikio, Ueda, Takanori
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2001
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926845/
https://ncbi.nlm.nih.gov/pubmed/11572766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2001.tb01188.x
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