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Close Correlation of 1‐β‐D‐Arabinofuranosylcytosine 5′‐Triphosphate, an Intracellular Active Metabolite, to the Therapeutic Efficacy of N(4)‐Behenoyl‐1‐β‐D‐arabinofuranosylcytosine Therapy for Acute Myelogenous Leukemia
N(4)‐Behenoyl‐l‐β‐D‐arabinofuranosylcytosine (BHAC), a prodrug of 1‐β ‐D‐arabinofuranosylcy‐tosine, is used effectively for the treatment of leukemia in Japan. BHAC therapy may be more effective if it is delivered in conjunction with monitoring of 1‐β ‐D‐arabinofuranosylcytosine 5′‐tri‐phosphate (ar...
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Publicat a: | Jpn J Cancer Res |
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Autors principals: | , , , , , , , , , , , |
Format: | Artigo |
Idioma: | Inglês |
Publicat: |
Blackwell Publishing Ltd
2001
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5926845/ https://ncbi.nlm.nih.gov/pubmed/11572766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2001.tb01188.x |
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