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A Novel p.G141R Mutation in ILDR1 Leads to Recessive Nonsyndromic Deafness DFNB42 in Two Chinese Han Families

Genetic hearing impairment is highly heterogeneous. In this study, targeted next-generation sequencing (NGS) in two Chinese Han families identified a novel p.G141R homozygous mutation in ILDR1 as the genetic cause of the deafness. Consistent with the recessive inheritance, cosegregation of the p.G14...

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Detalhes bibliográficos
Publicado no:Neural Plast
Main Authors: Wang, Xueling, Wang, Longhao, Peng, Hu, Yang, Tao, Wu, Hao
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926476/
https://ncbi.nlm.nih.gov/pubmed/29849566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/7272308
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