More Frequent β‐Catenin Gene Mutations in Adenomas than in Aberrant Crypt Foci or Adenocarcinomas in the Large Intestines of 2‐Amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (PhIP)‐treated Rats

Alteration of adenomatous polyposis coli (APC) is known to be an early event in neoplasia, causing activation of the β‐catenin/Tcf pathway. Although it is thought that alterations in APC and β‐catenin may complement one another, the contribution of β‐catenin mutations to colorectal carcino‐genesis r...

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Detalles Bibliográficos
Publicado en:Jpn J Cancer Res
Main Authors: Tsukamoto, Tetsuya, Tanaka, Harunari, Fukami, Hiroko, Inoue, Manami, Takahashi, Mami, Wakabayashi, Keiji, Tatematsu, Masae
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2000
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926430/
https://ncbi.nlm.nih.gov/pubmed/10965019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb01015.x
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