Effective Cancer Targeting Using an Anti‐tumor Tissue Vascular Endotheliumspecific Monoclonal Antibody (TES‐23)

Immunoconjugate targeting of solid tumors has not been routinely successful because the endothelial cells of blood vessels act as a physical barrier against the transport of macromolecules, such as antibodies. In the present study, we attempted to achieve tumor vascular targeting with an antitumor t...

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Veröffentlicht in:Jpn J Cancer Res
Hauptverfasser: Wakai, Yukiko, Matsui, Junji, Koizumi, Keiichi, Tsunoda, Shin‐ichi, Makimoto, Hiroo, Ohizumi, Iwao, Taniguchi, Kenji, Kaiho, Shin‐ichi, Saito, Hiroyuki, Utoguchi, Naoki, Tsutsumi, Yasuo, Nakagawa, Shinsaku, Ohsugi, Yoshiyuki, Mayumi, Tadanori
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2000
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926302/
https://ncbi.nlm.nih.gov/pubmed/11123432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb00920.x
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