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Nrf2 Deficiency Promotes Melanoma Growth and Lung Metastasis
The role of Nrf2, a key regulator of antioxidant and cytoprotective genes, in tumorigenesis remains controversial. Here we showed that Nrf2 deficiency led to increased local tumor growth in mice following subcutaneous injection of B16-F10 melanoma cells, as indicated by increased proportion of anima...
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| Publicado no: | React Oxyg Species (Apex) |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5926243/ https://ncbi.nlm.nih.gov/pubmed/29721548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20455/ros.2016.853 |
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