Development and Distribution of 2‐Amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]‐pyridine (PhIP)‐induced Aberrant Crypt Foci in the Rat Large Intestine

Aberrant crypt foci (ACF) are generally considered to be preneoplastic lesions for colon cancer. To assess their induction by 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (PhIP), a colon carcinogen, we performed a sequential study of ACF morphology and localization. F344 male rats were given PhIP...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Principais autores: Tsukamoto, Tetsuya, Kozaki, Ken‐ichi, Nishikawa, Yoko, Yamamoto, Masami, Fukami, Hiroko, Inoue, Manami, Wakabayashi, Keiji, Tatematsu, Masae
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1999
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926130/
https://ncbi.nlm.nih.gov/pubmed/10470283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1999.tb00806.x
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