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Effect of 5‐Fluorouracil on Cell Cycle Regulatory Proteins in Human Colon Cancer Cell Line

We investigated the effects of 5‐fluorouracil (5‐FU) on cell cycle‐regulating proteins in RPMI 4788 cells. 5‐FU inhibited cell growth dose‐dependently and this growth inhibition was accompanied with cell cycle accumulation in early S phase and increased expression of cyclin A. When cells were releas...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Takeda, Haruo, Haisa, Minoru, Naomoto, Yoshio, Kawashima, Ryuichi, Satomoto, Kazutaka, Yamatuji, Tomoki, Tanaka, Noriaki
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926118/
https://ncbi.nlm.nih.gov/pubmed/10429661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1999.tb00800.x
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