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A Selective Cyclooxygenase‐2 Inhibitor Suppresses Tumor Growth in Nude Mouse Xenografted with Human Head and Neck Squamous Carcinoma Cells

The anti‐tumor effect of a selective cyclooxygenase (COX)‐2 inhibitor, JTE‐522, was examined with the human head and neck squamous cell carcinoma cell line KB. KB cells do not produce prostaglandin (PG)‐E2. In vitro, JTE‐522 induced an increase of G1 phase‐arrested cells, suppression of platelet‐der...

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Dades bibliogràfiques
Publicat a:Jpn J Cancer Res
Autors principals: Nishimura, Goshi, Yanoma, Syunsuke, Mizuno, Hiromi, Kawakami, Koji, Tsukuda, Mamoru
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 1999
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5925997/
https://ncbi.nlm.nih.gov/pubmed/10595745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1999.tb00690.x
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