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Promotion by Sodium L‐Ascorbate in Rat Two‐stage Urinary Bladder Carcinogenesis is Dependent on the Interval of Administration

In our two‐stage model of rat urinary bladder carcinogenesis employing N‐butyl‐N‐(4‐hydroxybutyl)nitrosamine (BBN) as the initiator, sodium L‐ascorbate (Na‐AsA) exhibits dose‐dependent promotion. In the present study, in order to assess the possible reversibility of the promoting effects, we investi...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Chen, Tian‐Xin, Wanibuchi, Hideki, Murai, Takashi, Kitano, Mitsuaki, Yamamoto, Shinji, Fukushima, Shoji
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5925984/
https://ncbi.nlm.nih.gov/pubmed/10076560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1999.tb00660.x
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