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Promotion by Sodium L‐Ascorbate in Rat Two‐stage Urinary Bladder Carcinogenesis is Dependent on the Interval of Administration

In our two‐stage model of rat urinary bladder carcinogenesis employing N‐butyl‐N‐(4‐hydroxybutyl)nitrosamine (BBN) as the initiator, sodium L‐ascorbate (Na‐AsA) exhibits dose‐dependent promotion. In the present study, in order to assess the possible reversibility of the promoting effects, we investi...

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Dettagli Bibliografici
Pubblicato in:Jpn J Cancer Res
Autori principali: Chen, Tian‐Xin, Wanibuchi, Hideki, Murai, Takashi, Kitano, Mitsuaki, Yamamoto, Shinji, Fukushima, Shoji
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5925984/
https://ncbi.nlm.nih.gov/pubmed/10076560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1999.tb00660.x
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