Transformation to small cell lung cancer after first-line afatinib treatment

Acquiring resistance to epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) is inevitable. Transformation to small cell lung cancer (SCLC) is reported as a possible mechanism of this acquired resistance. We describe the case of a 35-year-old man with lung adenocarcinoma harbori...

Full description

Saved in:
Bibliographic Details
Published in:Respir Med Case Rep
Main Authors: Shiroyama, Takayuki, Nasu, Shingo, Tanaka, Ayako, Takata, So, Masuhiro, Kentaro, Takada, Hiromune, Morita, Satomu, Morishita, Naoko, Suzuki, Hidekazu, Okamoto, Norio, Kawahara, Kunimitsu, Hirashima, Tomonori
Format: Artigo
Language:Inglês
Published: Elsevier 2018
Subjects:
Case Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5925950/
https://ncbi.nlm.nih.gov/pubmed/29719814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.rmcr.2018.02.011
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items