Transformation to small cell lung cancer after first-line afatinib treatment

Acquiring resistance to epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) is inevitable. Transformation to small cell lung cancer (SCLC) is reported as a possible mechanism of this acquired resistance. We describe the case of a 35-year-old man with lung adenocarcinoma harbori...

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Detalhes bibliográficos
Publicado no:Respir Med Case Rep
Main Authors: Shiroyama, Takayuki, Nasu, Shingo, Tanaka, Ayako, Takata, So, Masuhiro, Kentaro, Takada, Hiromune, Morita, Satomu, Morishita, Naoko, Suzuki, Hidekazu, Okamoto, Norio, Kawahara, Kunimitsu, Hirashima, Tomonori
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5925950/
https://ncbi.nlm.nih.gov/pubmed/29719814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.rmcr.2018.02.011
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