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Missing value imputation for LC-MS metabolomics data by incorporating metabolic network and adduct ion relations

MOTIVATION: Metabolomics data generated from liquid chromatography-mass spectrometry platforms often contain missing values. Existing imputation methods do not consider underlying feature relations and the metabolic network information. As a result, the imputation results may not be optimal. RESULTS...

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Enregistré dans:
Détails bibliographiques
Publié dans:Bioinformatics
Auteurs principaux: Jin, Zhuxuan, Kang, Jian, Yu, Tianwei
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5925787/
https://ncbi.nlm.nih.gov/pubmed/29272352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx816
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