N‐methyl‐D‐aspartate receptor antibody production from germinal center reactions: Therapeutic implications

INTRODUCTION: N‐methyl‐D‐aspartate receptor (NMDAR) antibody encephalitis is mediated by immunoglobulin G (IgG) autoantibodies directed against the NR1 subunit of the NMDAR. Around 20% of patients have an underlying ovarian teratoma, and the condition responds to early immunotherapies and ovarian te...

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Detalhes bibliográficos
Publicado no:Ann Neurol
Main Authors: Makuch, Mateusz, Wilson, Robert, Al‐Diwani, Adam, Varley, James, Kienzler, Anne‐Kathrin, Taylor, Jennifer, Berretta, Antonio, Fowler, Darren, Lennox, Belinda, Leite, M. Isabel, Waters, Patrick, Irani, Sarosh R
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5925521/
https://ncbi.nlm.nih.gov/pubmed/29406578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25173
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