Silencing Histone Deacetylase 7 Alleviates Transforming Growth Factor-β1-Induced Profibrotic Responses in Fibroblasts Derived from Peyronie's Plaque

PURPOSE: Epigenetic modifications, such as histone acetylation/deacetylation and DNA methylation, play a crucial role in the pathogenesis of inflammatory disorders and fibrotic diseases. The aim of this study was to study the differential gene expression of histone deacetylases (HDACs) in fibroblast...

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Vydáno v:World J Mens Health
Hlavní autoři: Kang, Dong Hyuk, Yin, Guo Nan, Choi, Min-Ji, Song, Kang-Moon, Ghatak, Kalyan, Minh, Nguyen Nhat, Kwon, Mi-Hye, Seong, Do-Hwan, Ryu, Ji-Kan, Suh, Jun-Kyu
Médium: Artigo
Jazyk:Inglês
Vydáno: Korean Society for Sexual Medicine and Andrology 2018
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924955/
https://ncbi.nlm.nih.gov/pubmed/29706035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5534/wjmh.170005
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