Neddylation mediates ventricular chamber maturation through repression of Hippo signaling

During development, ventricular chamber maturation is a crucial step in the formation of a functionally competent postnatal heart. Defects in this process can lead to left ventricular noncompaction cardiomyopathy and heart failure. However, molecular mechanisms underlying ventricular chamber develop...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Zou, Jianqiu, Ma, Wenxia, Li, Jie, Littlejohn, Rodney, Zhou, Hongyi, Kim, Il-man, Fulton, David J. R., Chen, Weiqin, Weintraub, Neal L., Zhou, Jiliang, Su, Huabo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2018
Gaiak:
PNAS Plus
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924905/
https://ncbi.nlm.nih.gov/pubmed/29632206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1719309115
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