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Neddylation mediates ventricular chamber maturation through repression of Hippo signaling
During development, ventricular chamber maturation is a crucial step in the formation of a functionally competent postnatal heart. Defects in this process can lead to left ventricular noncompaction cardiomyopathy and heart failure. However, molecular mechanisms underlying ventricular chamber develop...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5924905/ https://ncbi.nlm.nih.gov/pubmed/29632206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1719309115 |
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