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Translation initiation in bacterial polysomes through ribosome loading on a standby site on a highly translated mRNA

During translation, consecutive ribosomes load on an mRNA and form a polysome. The first ribosome binds to a single-stranded mRNA region and moves toward the start codon, unwinding potential mRNA structures on the way. In contrast, the following ribosomes can dock at the start codon only when the fi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Andreeva, Irena, Belardinelli, Riccardo, Rodnina, Marina V.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924895/
https://ncbi.nlm.nih.gov/pubmed/29632209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1718029115
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