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Regulatory dendritic cells for promotion of liver transplant operational tolerance: rationale for a clinical trial and accompanying mechanistic studies

Dendritic cells (DC) are rare, bone marrow (BM)-derived innate immune cells that critically maintain self-tolerance in the healthy steady-state. Regulatory DC (DCreg) with capacity to suppress allograft rejection and promote transplant tolerance in pre-clinical models can readily be generated from B...

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Detalles Bibliográficos
Publicado en:Hum Immunol
Autores principales: Thomson, Angus W., Humar, Abhinav, Lakkis, Fadi G., Metes, Diana M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924712/
https://ncbi.nlm.nih.gov/pubmed/29100944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humimm.2017.10.017
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