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Quantitative analysis of catecholamines in the Pink1 −/− rat model of early-onset Parkinson disease

Parkinson disease (PD) related to homozygous mutations in the Pink1 gene is associated with nigrostriatal dopamine depletion and a wide range of sensorimotor deficits. In humans and animal models of PD, not all sensorimotor deficits are levodopa-responsive. We hypothesized that the underlying mechan...

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Detalhes bibliográficos
Publicado no:Neuroscience
Main Authors: Kelm-Nelson, Cynthia A., Trevino, Michael A., Ciucci, Michelle R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924710/
https://ncbi.nlm.nih.gov/pubmed/29496635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2018.02.027
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