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Palmitic acid induces neurotoxicity and gliatoxicity in SH-SY5Y human neuroblastoma and T98G human glioblastoma cells

BACKGROUND: Obesity-related central nervous system (CNS) pathologies like neuroinflammation and reactive gliosis are associated with high-fat diet (HFD) related elevation of saturated fatty acids like palmitic acid (PA) in neurons and astrocytes of the brain. METHODS: Human neuroblastoma cells SH-SY...

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Bibliografske podrobnosti
izdano v:PeerJ
Main Authors: Ng, Yee-Wen, Say, Yee-How
Format: Artigo
Jezik:Inglês
Izdano: PeerJ Inc. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924683/
https://ncbi.nlm.nih.gov/pubmed/29713567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.4696
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