Phenylthiazoles with tert-Butyl Side Chain: Metabolically Stable with Anti-Biofilm Activity

A new series of phenylthiazoles with t-butyl lipophilic component was synthesized and their antibacterial activity against a panel of multidrug-resistant bacterial pathogens was evaluated. Five compounds demonstrated promising antibacterial activity against methicillin-resistant staphylococcal strai...

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Bibliografiske detaljer
Udgivet i:Eur J Med Chem
Main Authors: Kotb, Ahmed, Abutaleb, Nader S., Seleem, Mohamed A., Hagras, Mohamed, Mohammad, Haroon, Bayoumi, Ashraf, Ghiaty, Adel, Seleem, Mohamed N., Mayhoub, Abdelrahman S.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924651/
https://ncbi.nlm.nih.gov/pubmed/29605807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2018.03.044
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