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Multimodal Neuroimaging and Behavioral Assessment of SNCA Polymorphism rs356219 in Older Adults

The single nucleotide polymorphism rs356219 in the α-synuclein (SNCA) gene has been shown to significantly contribute to an earlier age at onset of Parkinson's disease (PD), regulate SNCA expression in PD-brain regions, blood and plasma. Here, we used multimodal MRI to study healthy adults with...

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Bibliografiske detaljer
Udgivet i:Neurobiol Aging
Main Authors: Burciu, Roxana G., Seidler, Rachael D., Shukla, Priyank, Nalls, Mike A., Singleton, Andrew B., Okun, Michael S., Vaillancourt, David E.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924640/
https://ncbi.nlm.nih.gov/pubmed/29505953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2018.02.001
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