MR-Guided Delivery of AAV2-BDNF into the Entorhinal Cortex of Non-Human Primates

Brain-derived neurotrophic factor (BDNF) gene delivery to the entorhinal cortex is a candidate for treatment of Alzheimer’s disease (AD) to reduce neurodegeneration that is associated with memory loss. Accurate targeting of the entorhinal cortex in AD is complex due to the deep and atrophic state of...

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Detalhes bibliográficos
Publicado no:Gene Ther
Main Authors: Nagahara, Alan H., Wilson, Bayard R., Ivasyk, Iryna, Kovacs, Imre, Rawalji, Saytam, Bringas, John R., Pivirotto, Phillip J., Sebastian, Waldy San, Samaranch, Lluis, Bankiewicz, Krystof S., Tuszynski, Mark H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924461/
https://ncbi.nlm.nih.gov/pubmed/29535375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41434-018-0010-2
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