Delta / mu opioid receptor interactions in operant conditioning assays of pain-depressed responding and drug-induced rate suppression: Assessment of therapeutic index in male Sprague Dawley rats

RATIONALE AND OBJECTIVES: Although delta/mu receptor interactions vary as a function of behavioral endpoint, there have been no assessments of these interactions using assays of pain-depressed responding. This is the first report of delta/mu interactions using an assay of pain depressed behavior. ME...

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Publicado no:Psychopharmacology (Berl)
Main Authors: Cone, Katherine, Lanpher, Janell, Kinens, Abigail, Richard, Philomena, Couture, Sarah, Brackin, Rebecca, Payne, Emily, Harrington, Kylee, Rice, Kenner C., Stevenson, Glenn W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924452/
https://ncbi.nlm.nih.gov/pubmed/29572653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-018-4876-x
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