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Application of droplet digital PCR in the analysis of genome integration and organization of the transgene in BAC transgenic mice
Transgenic (Tg) mice containing bacterial artificial chromosome (BAC) DNA are widely used for gene expression analysis and gene therapy models because BAC transgenes provide gene expression at physiological levels with the same developmental timing as endogenous genes. To ensure correct interpretati...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5923295/ https://ncbi.nlm.nih.gov/pubmed/29703985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25001-x |
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