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Contribution of multidrug and toxin extrusion protein 1 (MATE1) to renal secretion of trimethylamine-N-oxide (TMAO)

Trimethylamine-N-oxide (TMAO) gained considerable attention because of its role as a cardiovascular risk biomarker. Organic cation transporter 2 (OCT2) mediates TMAO uptake into renal proximal tubular cells. Here we investigated the potential role of multidrug and toxin extrusion protein 1 (MATE1) f...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gessner, A., König, J., Fromm, M. F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5923289/
https://ncbi.nlm.nih.gov/pubmed/29704007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25139-8
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