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Efficacy of Human-Simulated Exposures of Ceftolozane-Tazobactam Alone and in Combination with Amikacin or Colistin against Multidrug-Resistant Pseudomonas aeruginosa in an In Vitro Pharmacodynamic Model

Combination therapy is an attractive option for the treatment of multidrug-resistant (MDR) Pseudomonas aeruginosa infections; however, limited data are available on combinations with ceftolozane-tazobactam (C-T). The in vitro pharmacodynamic chemostat model was employed to compare human-simulated ex...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Rico Caballero, Veronica, Almarzoky Abuhussain, Safa, Kuti, Joseph L., Nicolau, David P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5923128/
https://ncbi.nlm.nih.gov/pubmed/29483119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02384-17
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