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Targeting the Nonmevalonate Pathway in Burkholderia cenocepacia Increases Susceptibility to Certain β-Lactam Antibiotics

The nonmevalonate pathway is the sole pathway for isoprenoid biosynthesis in Burkholderia cenocepacia and is possibly a novel target for the development of antibacterial chemotherapy. The goals of the present study were to evaluate the essentiality of dxr, the second gene of the nonmevalonate pathwa...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Sass, Andrea, Everaert, Annelien, Van Acker, Heleen, Van den Driessche, Freija, Coenye, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5923124/
https://ncbi.nlm.nih.gov/pubmed/29439968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02607-17
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