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Coexistence of Two bla(NDM-5) Genes on an IncF Plasmid as Revealed by Nanopore Sequencing

In a carbapenem-resistant Escherichia coli clinical isolate of sequence type 167, two copies of bla(NDM-5) were found on a 144,225-bp IncF self-transmissible plasmid of the F36:A4:B(−) type. Both bla(NDM-5) genes were located in 11,065-bp regions flanked by two copies of IS26. The two regions were i...

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Pubblicato in:Antimicrob Agents Chemother
Autori principali: Feng, Yu, Liu, Lu, McNally, Alan, Zong, Zhiyong
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5923099/
https://ncbi.nlm.nih.gov/pubmed/29439976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00110-18
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