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Mutations in the Basic Region of the Mason-Pfizer Monkey Virus Nucleocapsid Protein Affect Reverse Transcription, Genomic RNA Packaging, and the Virus Assembly Site

In addition to specific RNA-binding zinc finger domains, the retroviral Gag polyprotein contains clusters of basic amino acid residues that are thought to support Gag-viral genomic RNA (gRNA) interactions. One of these clusters is the basic K(16)NK(18)EK(20) region, located upstream of the first zin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Dostálková, Alžběta, Kaufman, Filip, Křížová, Ivana, Kultová, Anna, Strohalmová, Karolína, Hadravová, Romana, Ruml, Tomáš, Rumlová, Michaela
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5923082/
https://ncbi.nlm.nih.gov/pubmed/29491167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00106-18
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