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Performance of next-generation sequencing on small tumor specimens and/or low tumor content samples using a commercially available platform

BACKGROUND: Next generation sequencing tests (NGS) are usually performed on relatively small core biopsy or fine needle aspiration (FNA) samples. Data is limited on what amount of tumor by volume or minimum number of FNA passes are needed to yield sufficient material for running NGS. We sought to id...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Morris, Scott, Subramanian, Janakiraman, Gel, Esma, Runger, George, Thompson, Eric, Mallery, David, Weiss, Glen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922576/
https://ncbi.nlm.nih.gov/pubmed/29702695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196556
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