Impact of mutational studies on the diagnosis and the outcome of high-risk myelodysplastic syndromes and secondary acute myeloid leukemia patients treated with 5-azacytidine

Myelodysplastic syndromes (MDS) are stem cell disorders caused by various gene abnormalities. We performed targeted deep sequencing in 39 patients with high-risk MDS and secondary acute myeloid leukemia (sAML) at diagnosis and follow-up (response and/or relapse), with the aim to define their mutatio...

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Publicado en:Oncotarget
Autores principales: Cabezón, Marta, Bargay, Joan, Xicoy, Blanca, García, Olga, Borrás, Josep, Tormo, Mar, Marcé, Sílvia, Pedro, Carme, Valcárcel, David, Jiménez, Maria-José, Guàrdia, Ramón, Palomo, Laura, Brunet, Salut, Vall-Llovera, Ferran, Garcia, Antoni, Feliu, Evarist, Zamora, Lurdes
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922401/
https://ncbi.nlm.nih.gov/pubmed/29721207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25046
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