Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) is a novel marker for patients with BRAF-mutated metastatic melanoma

Metastatic melanoma carrying BRAF mutations represent a still unmet medical need as success of BRAF inhibitors is limited by development of resistance. Nicotinamide phosphoribosyltransferase (NAMPT) is a key enzyme in NAD biosynthesis. An extracellular form (eNAMPT) possesses cytokine-like functions...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Audrito, Valentina, Managò, Antonella, Zamporlini, Federica, Rulli, Eliana, Gaudino, Federica, Madonna, Gabriele, D'Atri, Stefania, Antonini Cappellini, Gian Carlo, Ascierto, Paolo Antonio, Massi, Daniela, Raffaelli, Nadia, Mandalà, Mario, Deaglio, Silvia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2018
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922372/
https://ncbi.nlm.nih.gov/pubmed/29721178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24871
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