Isolated metastasis of an EGFR-L858R-mutated NSCLC of the meninges: the potential impact of CXCL12/CXCR4 axis in EGFR(mut) NSCLC in diagnosis, follow-up and treatment

Brain and leptomeningeal metastasis (LMM) of non-small cell lung cancer is still associated with poor prognosis. Moreover, the current diagnostic standard for LMM often yields false negative results and the scientific progress in this field is still unsatisfying. We present a case of a 71-year old p...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lüke, Florian, Blazquez, Raquel, Yamaci, Rezan Fahrioglu, Lu, Xin, Pregler, Benedikt, Hannus, Stefan, Menhart, Karin, Hellwig, Dirk, Wester, Hans-Jürgen, Kropf, Saskia, Heudobler, Daniel, Grosse, Jirka, Moosbauer, Jutta, Hutterer, Markus, Hau, Peter, Riemenschneider, Markus J., Bayerlová, Michaela, Bleckmann, Annalen, Polzer, Bernhard, Beißbarth, Tim, Klein, Christoph A., Pukrop, Tobias
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922360/
https://ncbi.nlm.nih.gov/pubmed/29721166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24787
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