Gut microbial RNA and DNA analysis predicts hospitalizations in cirrhosis

BACKGROUND. Cirrhosis is associated with gut microbial changes, but current 16S rDNA techniques sequence both dead and live bacteria. We aimed to determine the rRNA content compared with DNA from the same stool sample to evaluate cirrhosis progression and predict hospitalizations. METHODS. Cirrhotic...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Bajaj, Jasmohan S., Thacker, Leroy R., Fagan, Andrew, White, Melanie B., Gavis, Edith A., Hylemon, Phillip B., Brown, Robert, Acharya, Chathur, Heuman, Douglas M., Fuchs, Michael, Dalmet, Swati, Sikaroodi, Masoumeh, Gillevet, Patrick M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Clinical Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922291/
https://ncbi.nlm.nih.gov/pubmed/29515036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.98019
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