Gut microbial RNA and DNA analysis predicts hospitalizations in cirrhosis

BACKGROUND. Cirrhosis is associated with gut microbial changes, but current 16S rDNA techniques sequence both dead and live bacteria. We aimed to determine the rRNA content compared with DNA from the same stool sample to evaluate cirrhosis progression and predict hospitalizations. METHODS. Cirrhotic...

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Dettagli Bibliografici
Pubblicato in:JCI Insight
Autori principali: Bajaj, Jasmohan S., Thacker, Leroy R., Fagan, Andrew, White, Melanie B., Gavis, Edith A., Hylemon, Phillip B., Brown, Robert, Acharya, Chathur, Heuman, Douglas M., Fuchs, Michael, Dalmet, Swati, Sikaroodi, Masoumeh, Gillevet, Patrick M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2018
Soggetti:
Clinical Medicine
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922291/
https://ncbi.nlm.nih.gov/pubmed/29515036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.98019
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