Physiological mechanisms of sustained fumagillin-induced weight loss

Current obesity interventions suffer from lack of durable effects and undesirable complications. Fumagillin, an inhibitor of methionine aminopeptidase-2, causes weight loss by reducing food intake, but with effects on weight that are superior to pair-feeding. Here, we show that feeding of rats on a...

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Vydáno v:JCI Insight
Hlavní autoři: An, Jie, Wang, Liping, Patnode, Michael L., Ridaura, Vanessa K., Haldeman, Jonathan M., Stevens, Robert D., Ilkayeva, Olga, Bain, James R., Muehlbauer, Michael J., Glynn, Erin L., Thomas, Steven, Muoio, Deborah, Summers, Scott A., Vath, James E., Hughes, Thomas E., Gordon, Jeffrey I., Newgard, Christopher B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922281/
https://ncbi.nlm.nih.gov/pubmed/29515039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99453
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