rhACE2 Therapy Modifies Bleomycin-Induced Pulmonary Hypertension via Rescue of Vascular Remodeling

Background: Pulmonary hypertension (PH) is a progressive cardiovascular disease, characterized by endothelial and smooth muscle dysfunction and vascular remodeling, followed by right heart failure. Group III PH develops secondarily to chronic lung disease such as idiopathic pulmonary fibrosis (IPF),...

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Vydáno v:Front Physiol
Hlavní autoři: Rathinasabapathy, Anandharajan, Bryant, Andrew J., Suzuki, Toshio, Moore, Christy, Shay, Sheila, Gladson, Santhi, West, James D., Carrier, Erica J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Physiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922219/
https://ncbi.nlm.nih.gov/pubmed/29731719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00271
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