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Regulation of calretinin in malignant mesothelioma is mediated by septin 7 binding to the CALB2 promoter

BACKGROUND: The calcium-binding protein calretinin (gene name: CALB2) is currently considered as the most sensitive and specific marker for the diagnosis of malignant mesothelioma (MM). MM is a very aggressive tumor strongly linked to asbestos exposure and with no existing cure so far. The mechanism...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Blum, Walter, Pecze, László, Rodriguez, Janine Wörthmüller, Steinauer, Martine, Schwaller, Beat
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922012/
https://ncbi.nlm.nih.gov/pubmed/29699512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4385-7
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