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Caspase‐3 Activation Is Not Responsible for Vinblastine‐induced Bcl‐2 Phosphorylation and G2/M Arrest in Human Small Cell Lung Carcinoma Ms‐1 Cells

Vinblastine arrests cells in the G2/M phase of the cell cycle and subsequently induces cell death by apoptosis. We found that treatment of cells with vinblastine induced phosphorylation of Bcl‐2, resulting in the dissociation of Bcl‐2 and Bax. Moreover, vinblastine‐induced apoptosis was suppressed b...

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Bibliografske podrobnosti
izdano v:Jpn J Cancer Res
Main Authors: Tashiro, Etsu, Simizu, Siro, Takada, Minoru, Umezawa, Kazuo, Imoto, Masaya
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 1998
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921943/
https://ncbi.nlm.nih.gov/pubmed/9818030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1998.tb00652.x
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