Rhenium‐186‐mercaptoacetyltriglycine‐labeled Monoclonal Antibody for Radioimmunotherapy: In vitro Assessment, in vivo Kinetics and Dosimetry in Tumor‐bearing Nude Mice

Stability and immunoreactivity of (186)Re‐labeled monoclonal antibody were examined, and its in vivo kinetics was investigated in tumor‐bearing Balb/c nu/nu female mice to assess the feasibility of using it in radioimmunotherapy (RIT). A murine IgG(1), A7, against a 45 kD glycoprotein in human colon...

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Udgivet i:Jpn J Cancer Res
Main Authors: Kinuya, Seigo, Yokoyama, Kunihiko, Tega, Harunobu, Hiramatsu, Takashi, Konishi, Shota, Yamamoto, Wakako, Shuke, Noriyuki, Aburano, Tamio, Watanabe, Naoto, Takayama, Terahiko, Michigishi, Takatoshi, Tonami, Norihisa
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 1998
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921918/
https://ncbi.nlm.nih.gov/pubmed/9765625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1998.tb00642.x
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