Cytotoxic Mechanisms of FK317, a New Class of Bioreductive Agent with Potent Antitumor Activity

FK317 is a member of a new class of bioreductive agents that exhibit strong cytotoxicity against various human cancer cells. The effect of FK317 was found to be stronger than that of mitomycin C (MMC), adriamycin (ADR) or cisplatin (CDDP). Alkaline elution analysis indicated that FK317 formed inters...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Naoe, Yoshinori, Inami, Masamichi, Kawamura, Ikuo, Nishigaki, Fusako, Tsujimoto, Susumu, Matsumoto, Sanae, Manda, Toshitaka, Shimomura, Kyoichi
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1998
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921879/
https://ncbi.nlm.nih.gov/pubmed/9703365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1998.tb03269.x
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