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Inhibition by Sphingosine of Leukemic Cell Killing by Human Monocytes Activated with Interleukin‐2: A Possible Role of Protein Kinase C

Sphingosine and its analogs, which inhibit protein kinase C (PKC), are known to be potent inducers of apoptosis in tumor cells. However, we were concerned that sphingosine might also interfere with anti‐tumor cells of the immune system. Therefore, we evaluated the effect of sphingosine on activation...

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Foilsithe in:Jpn J Cancer Res
Main Authors: Nakabo, Yukiharu, Pabst, Michael J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Blackwell Publishing Ltd 1998
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921842/
https://ncbi.nlm.nih.gov/pubmed/9685859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1998.tb03296.x
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