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Increased Sensitivity to Long‐term 5‐Fluorouracil Exposure of Human Colon Cancer HT‐29 Cells Resistant to Short‐term Exposure

A 5‐fluorouracil (5‐FU)‐resistant subline of human colon cancer HT‐29 cells was developed by repeated 1‐h exposure in vitro to 5‐FU. This subline (HT‐29/5‐FU/S) had 8‐fold resistance to 5‐FU in a 1‐h exposure assay. However, it had rather increased sensitivity to 5‐FU when assayed after a continuous...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Inaba, Makoto, Tanaka, Tomoko, Sawada, Hiroko
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921808/
https://ncbi.nlm.nih.gov/pubmed/9600127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1998.tb00565.x
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