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Tumor‐selective Distribution of an Active Metabolite of the 9‐Aminoanthracycline Amrubicin
It has been reported that the 9‐aminoanthracycline amrubicin shows good efficacy in human tumor xenograft models. We studied the disposition and metabolism of amrubicin in mice, in comparison with those of doxorubicin. Amrubicinol, a 13‐hydroxy metabolite of amrubicin, which is 10 to 100 times more...
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| Publicado no: | Jpn J Cancer Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5921696/ https://ncbi.nlm.nih.gov/pubmed/9849586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1998.tb00497.x |
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