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A Large Germline Deletion of the MEN1 Gene in a Family with Multiple Endocrine Neoplasia Type 1

Multiple endocrine neoplasia type 1 (MEN1) is a familial cancer syndrome inherited as an autosomal dominant trait. Various heterozygous germline mutations of the responsible gene, MEN1, have been identified within its exons in many, but not all, affected individuals. We here demonstrate, by DNA poly...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Kishi, Mari, Tsukada, Toshihiko, Shimizu, Satoko, Futami, Hitoyasu, Ito, Yukio, Kanbe, Masako, Obara, Takao, Yamaguchi, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921582/
https://ncbi.nlm.nih.gov/pubmed/9510467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1998.tb00470.x
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