Bortezomib enhances radiosensitivity in oral cancer through inducing autophagy-mediated TRAF6 oncoprotein degradation

BACKGROUND: Oral squamous cell carcinoma (OSCC) is a malignant tumor that may occur anywhere within the oral cavity. The survival rate of OSCC patients has not improved over the past decades due to its heterogeneous etiology, genetic aberrations, and treatment outcomes. We investigated the role of t...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Wu, Yuan-Hua, Wu, Wun-Syuan, Lin, Li-Ching, Liu, Chiang-Shin, Ho, Sheng-Yow, Wang, Bour-Jr, Huang, Bu-Miin, Yeh, Ya-Ling, Chiu, Hui-Wen, Yang, Wei-Lei, Wang, Ying-Jan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921410/
https://ncbi.nlm.nih.gov/pubmed/29703234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0760-0
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