Prevention by 2‐Mercaptoethane Sulfonate and N‐Acetylcysteine of Renal Oxidative Damage in Rats Treated with Ferric Nitrilotriacetate

Ferric nitrilotriacetate (Fe‐NTA) is a renal toxicant and carcinogen in rats and mice. We found that its administration results in formation of 4‐hydroxy‐2‐nonenal (HNE) in the renal proximal tubule cells of rats, and 8‐hydroxydeoxyguanosine (8‐OHdG) adducts in their DNA, suggesting a role for oxida...

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Bibliografski detalji
Izdano u:Jpn J Cancer Res
Glavni autori: Umemura, Takashi, Hasegawa, Ryuichi, Sai‐Kato, Kimie, Nishikawa, Akiyoshi, Furukawa, Fumio, Toyokuni, Shinya, Uchida, Koji, Inoue, Tohru, Kurokawa, Yuji
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 1996
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921195/
https://ncbi.nlm.nih.gov/pubmed/8878448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1996.tb02115.x
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