Absence of a Mutation of the p21/WAF1 Gene in Human Lung and Pancreatic Cancers

The expression of a negative regulator of the cell cycle, p21(WAF1) protein, is trans‐activated hy wild‐type p53, but not by the mutant protein. Therefore, mutations of the p53 and WAF1 genes may be complementary. We examined DNAs from 70 human primary lung (63 of NSCLC and 7 of SCLC) and 24 pancrea...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Shimizu, Tatsunori, Miwa, Wataru, Nakamori, Shoji, Ishikawa, Osamu, Konishi, Yoichi, Sekiya, Takao
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1996
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921085/
https://ncbi.nlm.nih.gov/pubmed/8613430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1996.tb00217.x
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